Guide to Take 1-866-856-2679 off - Popup Virus Removal

This pesky 1-866-856-2679 keeps popping up in my desktop telling which my computers infected and blah blah blah, the actual pop-ups keep telling me in order to download their particular software program and all sorts of that. Ive copied their site address along with place it on my small BLOCKED free windows virus removal web sites inside Internet Options, Ive raised my pop-ups bar in order to HIGH, nothings working! HELP!